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Alejandro Garnacho has been rested immediately by Ruud van Nistelrooy in his final match accountable for Manchester United.
The Dutchman has opted to play Amad and Marcus Rashford on the wings, with Rasmus Hojlund holding his place up entrance.
Amad scored twice for the Purple Devils on Thursday within the Europa League however had been a doubt for this recreation after choosing up a knock.
Bruno Fernandes will, as all the time, play within the quantity 10 function.
Elsewhere, Andre Onana is in purpose.
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Featured picture Naomi Baker through Getty Photographs